WAY 316606 hydrochloride | sFRP-1 Inhibitor CAS 1781835-02-6
- Wuhan Hengheda Pharm Co.,Ltd
- China
- Immediately after payment
- 500/g batch
Direct manufacture
Bulk quantity
Min 98%
Free samples
Product Name | WAY 316606 hcl |
Brand | HHDPHARM |
CAS No. | 1781835-02-6 |
| Appearance | White powders |
Storage | Room temperaure |
MF | C18H20ClF3N2O4S2 |
Shelf Life | 2 yeaars |
Purity | 99% |
| Solubility | Soluble in DMSO |
| Grade | Enterprise Standard |
Potent and water soluble inhibitor of secreted Frizzled-Related Protein I (sFRP-1; Kd value 0.08 μM and EC50 value 0.65 μM for Wnt-luciferase activity from U2-OS cells) that stimulates the Wnt/β-catenin canonical signaling pathway. WAY316606 increased total bone area in a murine calvarial organ culture assay at concentrations as low as 0.0001 μM. WAY-316606 also bound to sFRP-2, albeit over 10 times weaker (Kd value 1.0 μM) and shows moderate to low inhibition of cytochrome p450 isozymes (3A4, 2D6, 2C9) and good stability in rat and human liver microsomes (t1/2 > 60 min in each species).
Do we have the test reports for our products provided by the independent third party?
Every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA. Our products were also tested by American Analytical Chemistry Laboratories and Chromadex too....more
Every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA. Our products were also tested by American Analytical Chemistry Laboratories and Chromadex too....more
