WAY 262611 dihydrochloride | DKK1 inhibitor | WAY262611 CAS 2108968-58-5
- Wuhan Hengheda Pharm Co.,Ltd
- China
- Immediately after payment
- 500/g batch
Direct manufacture
Bulk quantity
Min 98%
Free samples
Product Name | WAY262611 Dihydrochloride |
Brand | HHDPHARM |
CAS No. | 2108968-58-5 |
Appearance | White powders |
Storage | Room temperaure |
MF | C20H22N4.2HCl |
Shelf Life | 2 yeaars |
Purity | 99% |
Solubility | Soluble in water and DMSO |
Grade | Enterprise Standard |
Inhibitor of Dickkopf-1 (DKK1); WAY 262611 is a wingless Wnt/β-Catenin signaling agonist with an inhibitory effect on DKK1, displaying an EC50 value of 0.63 μM for DKK1-mediated TCF-Luciferase, no affinity for GSK-3β (IC50 value >100 μM) and enhancing the bone formation rate in ovariectomized (OVX) rats following oral adminstration. Dickkopf-1 (DKK1) is a soluble inhibitor of Wnt-3a mediated Wnt/β-catenin signaling required for embryonic head development. It regulates Wnt signaling by binding to the Wnt coreceptor lipoprotein-related protein-5 (LRP5)/Arrow, and Kremen2 (Kr2) simultaneously.
Do we have the test reports for our products provided by the independent third party?
Every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA. Our products were also tested by American Analytical Chemistry Laboratories and Chromadex too....more
Every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA. Our products were also tested by American Analytical Chemistry Laboratories and Chromadex too....more