nmn

  • Beta NMN/BETA-NICOTINAMIDE Nicotinatmide Mononucleotide CAS1094-61-7

    Beta NMN Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (Beta-NMN)-activated RNA fragments. Nicotinamide mononucleotide in human cells play an important role in energy generation, it involved in intracellular NAD (nicotinamide adenine dinucleotide, cell energy conversion important coenzyme) synthesis, used in anti-aging, fall blood sugar and other health care products. Nicotinamide Mononucleotide widely used for cosmetics and pharmaceutical.In cosmetics has anti-aging and anti-allergic agents effects etc.

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  • NADH/beta-Nicotinamide Adenine Dinucleotide Disodium Salt(NADH 3Na) CAS 606-68-8

    NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NADH is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). It forms NADP with the addition of a phosphate group to the 2' position of the adenosyl nucleotide through an ester linkage. NADH is synthesized by the body and thus is not an essential nutrient. NADH does require the essential nutrient nicotinamide for its synthesis, and NADH role in energy production is certainly an essential one. In addition to NADH role in the mitochondrial electron transport chain, NADH is produced in the cytosol. The mitochondrial membrane is impermeable to NADH, and this permeability barrier effectively separates the cytoplasmic from the mitochondrial NADH pools. However, cytoplasmic NADH can be used for biologic energy production. This occurs when the malate-aspartate shuttle introduces reducing equivalents from NADH in the cytosol to the electron transport chain of the mitochondria. This shuttle mainly occurs in the liver and heart.

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  • NADP/Nicotinamide Adenine Dinucleotide Phosphate CAS 53-59-8

    Nicotinamide adenine dinucleotide (NAD) and its relative nicotinamide adenine dinucleotide phosphate (NADP) are two of the most important coenzymes in the cell. NADP is simply NAD with a third phosphate group attached as shown at the bottom of the figure. Enzymes which use NADP(H) as an electron acceptor or as a cofactor. Nicotinamide adenine dinucleotide phosphate, a redox coenzyme that participates in a variety of enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NADP+) and reduced (NADPH). Analogue of NAD, but NADPH is used extensively in biosynthetic, rather than catabolic pathways as well as in photosynthesis.

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