RU58841

  • Setipiprant CAS 866460-33-5 Hair Loss Treatment

    Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelionwhich acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). Setipiprant was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients,Setipiprant failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.

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  • RU58841 CAS 154992-24-2 Hair Regrowth

    RU58841 (also known as RU-58841, PSK-3841 or HMR-3841) is a compound that has been garnering attention for RU58841 phenomenal response to hair growth. Anti-androgens have potential to be used to treat some 'male' cancers such as prostate cancer, as well as possibly targeting skin conditions including acne and male-pattern baldness. RU58841 differs from other anti-androgens in that rather than trying to reduce or block the production of testosterone or DHT, it focuses on the testosterone receptor. RU58841 is a specific androgen receptor antagonist or a so called anti-androgen. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne.

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  • CB-03-01 CAS 19608-29-8 For Hair Loss Treatment

    CB-03-01 is a molecule that acts at the level of the skin androgen receptor, blocking dihydrotestosterone (DHT) from binding to the receptor in the cell. CB-03-01 has a unique mechanism that acts at the skin surface, and is quickly metabolized to free inactive cortexolone, a substance naturally found in the body. CB-03-01 has been evaluated in a variety of animal models as well as initial human trials in Europe for acne and androgenic alopecia. The results of these studies demonstrate that CB-03-01 appears to have potent anti-androgenic activity without significant local or systemic side effects.

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