hair loss treatment

  • Setipiprant CAS 866460-33-5 Hair Loss Treatment

    Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelionwhich acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). Setipiprant was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients,Setipiprant failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.

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  • CB-03-01 CAS 19608-29-8 For Hair Loss Treatment

    CB-03-01 is a molecule that acts at the level of the skin androgen receptor, blocking dihydrotestosterone (DHT) from binding to the receptor in the cell. CB-03-01 has a unique mechanism that acts at the skin surface, and is quickly metabolized to free inactive cortexolone, a substance naturally found in the body. CB-03-01 has been evaluated in a variety of animal models as well as initial human trials in Europe for acne and androgenic alopecia. The results of these studies demonstrate that CB-03-01 appears to have potent anti-androgenic activity without significant local or systemic side effects.

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  • WAY316606 CAS 915759-45-4 For Hair Loss Treatment

    WAY-316606 is a drug that was originally developed to help treat osteoporosis, a disease which weakens bones and makes them more fragile and likely to break. Lab tests found when the drug was used there was a significant increase in human hair growth within two days. WAY-316606 is a compound known as an inhibitor because it prevents a natural occurring protein from working. The protein it blocks is involved in killing off growth and is linked to male pattern balding.Scientists found through research that the drug targeted the same protein growth as a cancer drug called cyclosporine A (CsA) which has been used to suppress transplant rejection and cause rapid hair growth. However, CsA has a large number of side effects including high blood pressure, headaches, kidney problems and vomiting, making it unsuitable to treat hair-loss,Whereas WAY-316606 comes without the nasty side effects and makes it more suitable to treat baldness.

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