5-Aminolevulinic Acid

  • Pharm Intermediate 5-Aminolevulinic Acid, Hydrochloride Salt CAS NO 925-45-1

    Aminolevulinic acid (ALA) is synthesized in mitochondria from glycine and succinyl-CoA by ALA synthetase (ALAS). Inhibition of ALAD results in activation of ALAS which further results in ALA accumulation in blood, plasma, and urine, thereby making ALA also a critical biomarker of early biological effects of Pb (Saxena and Flora, 2004). Effect of lead on bone marrow is more precisely depicted by increased ALA in plasma or blood than in urine, although ALA-U has been a recommended biomarker of Pb exposure. However, it can be detected only when blood Pb levels exceed 35 μg/dL in adults and 25–75 μg/dL in children, rendering it incapable of detecting low-level toxicity. Increased circulating levels of ALA may also result in decreased GABA release, resulting in behavioral disorders

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    5-Aminolevulinic Acid Methyl Ester Hydrochloride CAS 79416-27-6

    We have larger stock for 5-Aminolevulinic acid methyl ester hydrochloride and can be sent out immediately once we get your payment 5-Aminolevulinic acid methyl ester hydrochloride Spec. Test SpecificationResult Appearance A white or off-white powderWhite powder Heavy Metals(Pb) ≤ 20ppm <20ppm Residual solvents Acetone ≤ 5000ppm 522ppm Loss on Drying ≤ 1.5% 0.26% Residue on Ignition ≤ 0.5% 0.2% Assay ≥ 98.0% 99.26% Conclusion:This product by inspection accords with the standard Corporation

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