• NR/Nicotinamide Ribose;NRC/Nicotinamide Riboside Chloride CAS 1341-23-7 CAS 23111-00-4
  • NR/Nicotinamide Ribose;NRC/Nicotinamide Riboside Chloride CAS 1341-23-7 CAS 23111-00-4
NR/Nicotinamide Ribose;NRC/Nicotinamide Riboside Chloride CAS 1341-23-7 CAS 23111-00-4
  • Wuhan Hengheda Pharm Co.,Ltd
  • China
  • Immediately after payment
  • 100kg/month

Nicotinamide Riboside is a natural ingredient that is found in milk. It is actually related to niacin and other forms of vitamin B3.
Nicotinamide Riboside has become more and more popular today because of various scientific studies that prove Nicotinamide Riboside ability to prevent obesity by helping you fight weight gain. Researchers have found that Nicotinamide Riboside can serve as a unique supplement that will boost one’s metabolism to help burn off more calories and prevent weight gain.
Apart from preventing weight gain,Nicotinamide Riboside also helps boost muscle performance, increase energy expenditure, and minimize the risk factors of diabetes.

Potential Benefits

Easily Converted Into NAD+

NAD+ is a coenzyme, or helper molecule, that takes part in many biological reactions.

While it’s essential for optimal health, research shows that NAD+ levels continue to fall with age. Low NAD+ levels are linked to poor aging and a variety of harmful diseases .

One way to raise NAD+ levels is to consume NAD+ precursors — the building blocks of NAD+ — such as nicotinamide riboside.

Animal studies show that nicotinamide riboside raises blood NAD+ levels by up to 2.7 times. What’s more, it’s more readily used by your body than other NAD+ precursors 

Activates Enzymes That May Promote Healthy Aging

Nicotinamide riboside helps increase NAD+ levels in your body.

In response, NAD+ activates certain enzymes that may promote healthy aging.

One group is sirtuins, which appear to improve lifespan and overall health in animals. Studies indicate that sirtuins may repair damaged DNA, boost stress resistance, reduce inflammation and offer other benefits that promote healthy aging .

Sirtuins are also responsible for the lifespan-extending benefits of calorie restriction Another group is Poly (ADP-Ribose) polymerases (PARPs), which repair damaged DNA. Studies link higher PARP activity to less DNA damage and a longer lifespan .

May Help Protect Brain Cells

NAD+ plays a key role in helping your brain cells age well.

Within brain cells, NAD+ helps control the production of PGC-1-alpha, a protein that appears to help protect cells against oxidative stress and impaired mitochondrial function .

Researchers believe both oxidative stress and impaired mitochondrial function are linked to age-related brain disorders such as Alzheimer’s and Parkinson’s disease .

In mice with Alzheimer’s disease, nicotinamide riboside raised brain NAD+ levels and PGC-1-alpha production by up to 70% and 50%, respectively. By the end of the study, the mice performed significantly better in memory-based tasks .

In a test-tube study, nicotinamide riboside raised NAD+ levels and significantly improved mitochondrial function in stem cells taken from a Parkinson’s disease patient .

However, it’s still not clear how helpful it is to raise NAD+ levels in people with age-related brain disorders. More human studies are needed.

May Lower Heart Disease Risk

Aging is a major risk factor for heart disease, which is the world's leading cause of death .

It can cause blood vessels like your aorta to become thicker, stiffer and less flexible.

Such changes can raise blood pressure levels and make your heart work harder.

In animals, raising NAD+ helped reverse age-related changes to arteries. nicotinamide riboside raised NAD+ levels, helped reduce stiffness in the aorta and lowered systolic blood pressure in adults at risk of high blood pressure 

That said, more human research is needed.

Other Potential Benefits

In addition, nicotinamide riboside may provide several other benefits:

  • May aid weight loss: Nicotinamide riboside helped speed up the metabolism of mice. However, it’s unclear whether it would have the same effect in humans and how strong this effect really is .

  • May lower cancer risk: High NAD+ levels help protect against DNA damage and oxidative stress, which are linked to cancer development 

  • May help treat jet lag: NAD+ helps regulate your body’s internal clock, so taking niagen may help treat jet lag or other circadian rhythm disorders by resetting your body’s internal clock 

  • May promote healthy muscle aging: Raising NAD+ levels helped improve muscle function, strength and endurance in older mice 

Do we have the test reports for our products provided by the independent third party?
Every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA. Our products were also tested by American Analytical Chemistry Laboratories and Chromadex too....more
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