• NADH/beta-Nicotinamide Adenine Dinucleotide Disodium Salt(NADH 3Na) CAS 606-68-8
  • NADH/beta-Nicotinamide Adenine Dinucleotide Disodium Salt(NADH 3Na) CAS 606-68-8
NADH/beta-Nicotinamide Adenine Dinucleotide Disodium Salt(NADH 3Na) CAS 606-68-8
  • Wuhan Hengheda Pharm Co.,Ltd
  • China
  • Immediately after payment
  • 100kg/month

NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NADH is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). It forms NADP with the addition of a phosphate group to the 2' position of the adenosyl nucleotide through an ester linkage.

NADH is synthesized by the body and thus is not an essential nutrient. NADH does require the essential nutrient nicotinamide for its synthesis, and NADH role in energy production is certainly an essential one. In addition to NADH role in the mitochondrial electron transport chain, NADH is produced in the cytosol. The mitochondrial membrane is impermeable to NADH, and this permeability barrier effectively separates the cytoplasmic from the mitochondrial NADH pools. However, cytoplasmic NADH can be used for biologic energy production. This occurs when the malate-aspartate shuttle introduces reducing equivalents from NADH in the cytosol to the electron transport chain of the mitochondria. This shuttle mainly occurs in the liver and heart.

NADH/beta-Nicotinamide Adenine Dinucleotide Disodium Salt(NADH 3Na) CAS 606-68-8

Overview Information

NADH stands for "nicotinamide adenine dinucleotide (NAD) + hydrogen (H)." This chemical occurs naturally in the body and plays a role in the chemical process that generates energy. People use NADH supplements as medicine.

NADH is used for improving mental clarity, alertness, concentration, and memory; as well as for treating Alzheimer’s disease and dementia. Because of its role in energy production, NADH is also used for improving athletic performance and treating chronic fatigue syndrome (CFS).

Some people use NADH for treating high blood pressure, high cholesterol, jet lag, depression, and Parkinson’s disease; opposing alcohol’s effects on the liver; reducing signs of aging; and protecting against the side effects of an AIDS drug called zidovudine (AZT).

Healthcare providers sometimes give NADH by intramuscular (IM) or intravenous (IV) injection for Parkinson's disease and depression.

How does it work?

NADH produced by our bodies is involved in making energy in the body. While there is some evidence that suggests NADH supplements might reduce blood pressure, lower cholesterol, help chronic fatigue syndrome by providing energy, and increase nerve signals for people with Parkinson's disease, there isn't enough information to know for sure how or if these supplements work.


Possibly Effective for

  • Chronic fatigue syndrome (CFS). Some research shows that NADH might reduce symptoms of CFS. It has shown benefit on fatigue when used alone, in combination with coenzyme Q10, or as an adjunct to traditional medications.

Possibly Ineffective for

  • Mental decline (dementia) related to Alzheimer's disease and other conditions. Taking NADH does not seem to improve memory or mental function in people with dementia.

Insufficient Evidence for

  • Parkinson's disease. So far, study results don’t agree about the effectiveness of NADH in treating Parkinson’s disease.

  • Depression.

  • Jet lag.

  • High blood pressure.

  • Improving athletic performance.

  • Improving memory and concentration.

  • Reducing signs of aging.

  • Lowering cholesterol levels.

  • Opposing alcohol's effects on the liver.

  • Protecting against side effects of the drug zidovudine (AZT) used to treat AIDS.

  • Other conditions.

More evidence is needed to rate the effectiveness of NADH for these uses.


FAQ
Do we have the test reports for our products provided by the independent third party?
Every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA. Our products were also tested by American Analytical Chemistry Laboratories and Chromadex too....more
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